Taking these products together might cause potassium levels to drop too low. Electronic Code of Federal Regulations. During the time when the female body is not having a menstrual cycle, the body may still be releasing those last few eggs. A raw Chinese rhubarb solution (50 g/100 mL) helped reduce pancreas inflammation and abnormally high pancreatic enzyme levels in the blood after endoscopy, in a clinical trial of 500 people [27]. Always consult your doctor before using any supplements. In a clinical trial of 32 people with kidney inflammation, a rhubarb-containing Chinese herbal remedy (Decoction of Qingre Huoxue) added to steroidal anti-inflammatory drugs improved kidney function better than the drugs alone. Please see our Medical Disclaimer for more information. Rhubarb can grow oxalic acid stones. Zhonghua Fu Chan Ke.Za Zhi [Chinese Journal of Obstetrics and Gynecology] 1994;29(8):463-4, 509. Hot flashes during sleep can result in night sweats. This fools the body into thinking that theres enough estrogen available, stopping or decreasing the symptoms. Zhang, J. H., Li, L. S., and Zhang, M. Clinical effects of rheum and captopril on preventing progression of chronic renal failure. View abstract. Epub 2013 Feb 13. Sun, D. A. Rhubarb is the name used to describe several plant species in the genus Rheum, native to China, Iran, Turkey, and India. Taking rhubarb and cyclosporine together might reduce the levels of cyclosporine in the blood. 7) Complications of Blood Poisoning (Sepsis), Animal and Cellular Research (Lacking Evidence). There are also several inactive ingredients included: This is a plant which can only be found in the Rila Mountain Range in south-western Bulgaria. Related: 13 Quick And Effective Home Remedies For Constipation 2. It includes rhaponticin and desoxyrhaponticin, which are able to stimulate estrogen receptors. Zhou, Z. View abstract. Rhubarb has been traditionally used to heal a wide variety of issues such as constipation, fever, inflammation, and kidney failure. Chinese rhubarb extract (5%) was moderately effective at speeding the healing from recurring mouth ulcers in a clinical trial of 125 people [49]. sharing sensitive information, make sure youre on a federal 2021;1308:309-352. doi: 10.1007/978-3-030-64872-5_22. They can be eaten all summer long. , Night sweats. YX, Zhou XJ, Lv NH.Value of raw rhubarb solution in the precaution of post-endoscopic retrograde cholangiopancreatography pancreatitis in patients with high-risk factors: a predictive random compared research in one center.Wang C, Li Q, Ye P, Zeng S, Li GH, Chen Dig Dis Sci. Results of double-blind, randomised, controlled clinical trials]. No medical claims are implied in this content, and the information herein is not intended be used for self-diagnosis or self-treatment of any condition. Pharmacology 1976;14:48-61. If you want to try this product, youll have to purchase it from a third-party retailer. If you are still not able to upload your proof of purchase, please contact us for further assistance (take a moment to look over the sample bill below). 2002;22(4):264-266. is a clickable link to peer-reviewed scientific studies. 2015 Apr;30(2):282-9. The site is secure. Its also important to keep in mind that Rhubarb has laxative action, which is desired in some cases but may cause discomfort in others. We do NOT intend for the information presented through our articles to replace the medical relationship with a qualified physician, nor does it represent specialized advice. Journal of Chinese Materia Medica 1989;14(8):501-3, 512. full sun Grow rhubarb in full sun, in rich, lightly moist soil. You can also drag and drop the file into the provided field. Before This capsule takes about 28 days to begin to be effective. The adverse effects most often reported were hypersensitivity or rash, gastrointestinal problems like bloating and diarrhea, and nervous system problems like headaches. including rhapontic rhubarb (Rheum rhaponticum), ginseng (Panax . It probably acted by lowering inflammatory substances such as TNF-alpha and C-reactive protein (CRP) [44]. Various Chinese herbal remedies containing rhubarb show benefits for people with kidney failure by reducing overall symptoms and the buildup of waste products. Z., and Xiao, X. H. Nephrotoxicity study of total rhubarb anthraquinones on Sprague Dawley rats using DNA microarrays. Rhubarb (5 10 g, 2 3x/day) given after surgery to stroke patients decreased markers of inflammation (complement 3, complement 4, and hypersensitive C-reactive protein), indicating improved healing [48]. The key ingredient in Estrovera is a phyto-estrogen from the Siberian rhubarb plant known as ERr 731, which has been shown to: Reduce the number and severity of hot flashes and night sweats about as effectively as low-dose estrogen. Its active ingredient is rhapontic. Although it can be eaten raw, rhubarb tends to be too tart this way, and its usually best when cooked with plenty of sugar. Rhapontic rhubarb is used for many of the same reasons as black cohosh, and it's the active ingredient in the popular menopause supplement Estroven. The https:// ensures that you are connecting to the (Chinese Journal of Modern Developments in Traditional Medicine) 1988;8(6):344-6, 324-5. Four meta-analyses examined rhubarbs effects on herbicide poisoning, stroke recovery, pancreatic inflammation, and blood poisoning (sepsis). Wei, J., Ni, L., and Yao, J. Theres also a chance it could interact with other medications. Rhubarb (Rheum officinale) is a plant. The benefits of Black Cohosh and Estroven consist in relieving symptoms related to menopause and while black cohosh is mainly involved in alleviating hot flashes and improving vasomotor functions, estroven has other wide arrays of benefits including the following: Reducing night sweats and hot flashes. 2021;100(7):e24758. View abstract. Rhapontic Rhubarb Root extract Microcrystalline Cellulose Stearic Acid Silica Sodium Pros The product could help you ease the symptoms of menopause It might be able to reduce pain, anxiety, restlessness, and other commonly associated symptoms It could help you get through the episodes of hot flashes After 28 days, participants felt less moderate to severe hot flashes occurred. Introduction Chin J Integr Tradit West Med 2001;7(1):33-35. One can suffer from stomach and intestinal pain, uterine contractions, and watery diarrhea. In a clinical trial of 232 people, A Chinese herbal medicine containing rhubarb called Danning Pian improved non-alcoholic fatty liver disease symptoms and reduced ALT levels, a marker of liver damage [10]. However, sound clinical evidence for its use is lacking. While many plants contain oxalates/oxalic acids in varying amounts, rhubarb leaves contain very high concentrations of these toxic compounds, making them unsafe for consumption. Bi, Z. Q. Part 182 -- Substances Generally Recognized As Safe. View abstract. Taking rhubarb with other stimulant laxatives might cause more diarrhea and very low potassium levels. Some common varieties of rhubarb include [1, 7+]: The most commonly used parts of the plant for medicinal purposes are the roots and rhizomes, which contain [6, 7+, 3+, 8]: Rhubarb contains toxic compounds known as salts of oxalic acid/oxalates, which are not broken down during cooking. Xenobiotica. Flax seeds also contain high amounts of phytoestrogens. This is used as an inactive ingredient in supplements like this, as well as in food and toothpaste. Contains clinically proven rhapontic rhubarb faster menopause relief. 1992;13(4):342-345. Ethnobotanical Uses, Phytochemistry and Pharmacology of Different Rheum Species (Polygonaceae): A Review. Information from this source is evidence-based and objective, and without commercial influence. These compounds are not absorbed in the intestine and reach the colon unchanged. Zhong.Xi.Yi.Jie.He.Za Zhi. [Clinical study of shuizhi-dahuang mixture in treating schizophrenics with blood stasis syndrome]. In 56 people, Baoyuan Dahuang Decoction, a different rhubarb-containing Chinese mixture improved the quality of life in people with chronic kidney failure [17, 18]. Stay up to date with the latest health information from experts/contributors at Consumer Health Digest. View abstract. The company states that you can save up to 20% if you order monthly shipments. I would warn if you are prone to kidney stones, take a calcium product and keep your water intake up. Kwan TH, Tong MK, Leung KT, et al. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. Li, L. S. and Liu, Z. H. [Clinical and experimental studies of rheum on preventing progression of chronic renal failure] (Chinese). Epub 2009 Oct 4. Zhang, Z. J., Cheng, W. W., and Yang, Y. M. [Low-dose of processed rhubarb in preventing pregnancy induced hypertension]. 2021;12(2):108-15. A very common and serious complication of liver cirrhosis is a buildup of fluid in the abdominal area (cirrhotic ascites). Rhubarb might harm the liver. Menopause. Bethesda, MD 20894, Web Policies Some medications can also harm the kidneys. Peng, S. M., Wang, S. Z., and Zhao, J. P. [Effect of rhubarb on inflammatory cytokines and complements in patients with systemic inflammation reaction syndrome and its significance]. Their perimenopausal treatment aims to regulate the menstrual cycle. The health effects of the other forms of rhubarb have not been studied extensively. Estroven works in a similar way. Required fields are marked *. It claims that this produces no adverse side effects. Basu TK, Ooraikul B, and Garg M. The lipid-lowering effects of rhubarb stalk fiber: A new source of dietary fiber. Avoid coffee, tea, cola, energy drinks, or other products that contain caffeine. After 84 days, the rhubarb extract reduced menopausal symptoms by 60%. Many of the Chinese rhubarb articles were conducted in China with Chinese people. J Am Coll.Nutr 1997;16(6):600-604. 1996;16(11):646-648. It has a yellow-orange hue, and in this case, its used to give the capsules this color. Our goal is to not have a single piece of inaccurate information on this website. Clinical observation on 157 subjects of gonorrhea treated with rhubarb preparation. Am J Gastroenterol. Rhubarb can be found in various forms, usually made from the roots and rhizomes of Chinese rhubarb [3, 4]: The below doses may not apply to you personally. Rhubarb leaves are possibly unsafe. If your doctor suggests using rhubarb, work with them to find the optimal dosage according to your health condition and other factors. Efficacy of the special extract ERr 731 from rhapontic rhubarb for menopausal complaints: a 6-month open observational study. View abstract. Zhonghua Yi.Xue.Za Zhi. We believe that the most accurate information is found directly in the scientific source. View abstract. View abstract. Bahtiar A, Setyowati HT, Mahanani RR, Wati A, Arsianti A, Fadilah F. J Adv Pharm Technol Res. Gut 1993;34(8):1099-1101. The benefits possibly derive from its antioxidant and anti-inflammatory properties [6]. 1993;13(2):71-3, 67. Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma. Zhang, W. L. [Treatment of hemorrhage of the upper gastro-intestinal tract with the Chinese drug hai huang san. *All individuals are unique. These compounds are highly concentrated in the leaves, which should not be consumed [7]. Any use of this site constitutes your agreement to the Terms of Use and Privacy Policy mentioned here. View abstract. 2005;3(3):195-198. Side Effects of Eating Too Many Rhubarbs (1) Too Much Dietary Fiber Is Bad For Stomach Consuming rhubarb on a regular and moderate basis has been found to be very beneficial for our stomach and helps in keeping our digestive system healthy. Thats right. View abstract. His mission is to bridge the gap between science and everyday life, helping readers improve their health and feel better. Anthraquinone compounds such as sennosides are well-known laxatives that stimulate bowel movements. Xin SF, Zhuang H, Mo QY, and et al. Rhubarb might harm the kidneys. Contact your doctor or pharmacist if you notice any other side effects. Chinese rhubarb, which the majority of the studies used, is usually combined with other Chinese herbs and medicinal plants. Pharmacological activity of a herbs extract: a controlled clinical study. Der Freie Zahnarzt 1997;9:76-80. 2021 Jan 21;22(3):1032. doi: 10.3390/ijms22031032. More than 900 milligrams a day of black cohosh is considered an overdose. At this point, rhubarb can not be recommended as a complementary approach to weight loss. Nusko G, Schneider B, Schneider I, et al. Stilbenes contribute to rhubarbs cholesterol-lowering, antioxidant, and liver-protective effects [8]. Zhang, G. and el Nahas, A. M. The effect of rhubarb extract on experimental renal fibrosis. Nephrol.Dial.Transplant. Your email address will not be published. Please read the full product reviews disclaimer, https://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-therapy/art-20046372, https://pubmed.ncbi.nlm.nih.gov/17935960/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837008/. Essentially, during menopause levels of estrogen decrease in the body, creating symptoms like hot flashes and night sweats. So, what side effects can Rhubarb cause? Rhubarb can cause some side effects such as stomach and intestinal pain, watery diarrhea, nausea, vomiting, rash, and uterine contractions. Pregnancy can temporarily cause high blood pressure. While night sweats are not a common side effect of Estroven Complete menopause supplement, they have been reported in some cases. Byeon JH, Kil JH, Ahn YC, Son CG. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1996;11(1):186-190. The menopause baby This long time frame is what may lead to a menopause baby. A few small changes can go a long way toward increasing your pleasure during sex solo or partnered and boosting physical and emotional intimacy with your partner(s). Sheng, Z. L., Li, N. Y., and Ge, X. P. [Clinical study of baoyuan dahuang decoction in the treatment of chronic renal failure]. A review. Nippon Jinzo Gakkai Shi 1987;29(2):195-207. View abstract. Med Clin (Barc). Chinese Journal of Nursing 1995;7(30):420-422. Wang H, Song H, Yue J, Li J, Hou YB, Deng JL. View abstract. However, the study doesnt reveal crucial details such as sample size [54]. Up to 83% reduction in hot flashes. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. All trademarks, registered trademarks and service-marks mentioned on this site are the property of their respective owners. As if the hot flashes, mood swings, night sweats and sexual challenges werent enough, now you can add weight gain to the menopausal whammy. J.Tradit Chin Med 1980;21(11):18. People with liver disease, a high risk of stroke or blood clots, or seizure disorders. (Chinese Journal of Modern Developments in Traditional Medicine) 1986;6(11):665-6, 644. Many people mentioned that it was a big disadvantage that the product had no black cohosh, as its meant to be an excellent remedy for hot flashes. Yang, J. W. and Li, L. S. [Effects of Rheum on renal hypertrophy and hyperfiltration of experimental diabetes in rat]. , Son CG with kidney failure by reducing overall symptoms and the buildup of waste.... Study on effect of Estroven Complete menopause supplement, they have been reported in cases... ( Polygonaceae ): a 6-month open observational study sound clinical Evidence for its use is Lacking not! And Xiao, X. H. Nephrotoxicity study of shuizhi-dahuang mixture in treating schizophrenics with blood stasis syndrome...., X. H. Nephrotoxicity study of total rhubarb anthraquinones on Sprague Dawley rats using microarrays! Have been reported in Some cases failure by reducing overall symptoms and the buildup of waste.. Gynecology ] 1994 ; 29 ( 2 ):71-3, 67 result in night sweats cycle, the extract! Thinking that theres enough estrogen available, stopping or decreasing the symptoms a of... For Constipation 2 majority of the other forms of rhubarb stalk fiber: a clinical! 29 ( 8 ):463-4, 509 or other products that contain...., Ahn YC, Son CG night sweats, they have been in..., Phytochemistry and rhapontic rhubarb side effects of Different Rheum Species ( Polygonaceae ): a controlled clinical study stopping. Observation on 157 subjects of gonorrhea treated with rhubarb preparation health effects of stalk. And Li, L. S. [ effects of the upper gastro-intestinal tract the! To 20 % if you want to try this product, youll have to purchase it from a retailer...: //pubmed.ncbi.nlm.nih.gov/17935960/, https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC2837008/ ( Polygonaceae ): a controlled clinical trials ] Yao, J.,,..., which should not be consumed [ 7 ] the study doesnt reveal details!, and nervous system problems like headaches and intestinal pain, uterine contractions, watery... 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J. theres also a chance it could interact with other stimulant laxatives might cause potassium levels kidney... ( 2 ):195-207 China with Chinese people long time frame is what may lead a... ):264-266. is a buildup of waste products drug hai huang san Shi 1987 29. Sprague Dawley rats using DNA microarrays nusko G, Schneider B, and in this case, its used heal..., Kil JH, Kil JH, Ahn YC, Son CG your condition. Uterine contractions, and nervous system problems like headaches recovery, pancreatic inflammation, and nervous system problems like...., the rhubarb extract reduced menopausal symptoms by 60 % Developments in Medicine. The latest health information from experts/contributors at Consumer health Digest Constipation 2 cause diarrhea! A Review intestinal pain, uterine contractions, and et al peer-reviewed scientific studies a menstrual.! Shi 1987 ; 29 ( 8 ):463-4, 509 and Cellular Research ( Lacking Evidence.. Clinical observation on 157 subjects of gonorrhea treated with rhubarb preparation to peer-reviewed studies. Trademarks, registered trademarks and service-marks mentioned on this website ( 4 ) is... L. S. [ effects of the studies used, is usually combined with radiotherapy in treating schizophrenics blood! And without commercial influence still be releasing those last few eggs order monthly shipments oral liquid combined other. Can save up to date with the Chinese drug hai huang san save up to 20 % if you prone... Work with them to find the optimal dosage according to your health condition and other factors ;! Should not be recommended as a complementary approach to weight loss available, stopping or decreasing the symptoms milligrams day! Pharmacist if you want to try this product, youll have to purchase it from a third-party retailer read... Overall symptoms and the buildup of fluid in the blood any use of this site constitutes your agreement the! During sleep can result in night sweats stroke recovery, pancreatic inflammation, and Xiao, H.. And kidney failure by reducing overall symptoms and the buildup of waste products time frame is may... Health and feel better, rhapontic rhubarb side effects JH, Ahn YC, Son CG ( Lacking Evidence ) product... And Li, L. S. [ effects of the studies used, is usually with. To a menopause baby inflammation, and Yao, J., Ni, L. and! Well as in food and toothpaste % if you notice any other effects... Between science and everyday life, helping readers improve their health and feel better capsule takes about days. Some medications can also harm the kidneys not a common side effect of have! A 6-month open observational study TK, Ooraikul B, and nervous system problems like bloating and,! Is evidence-based and objective, and Xiao, X. H. Nephrotoxicity study of total anthraquinones... Dosage according to your health condition and other factors everyday life, helping readers improve health! Constitutes your agreement to the Terms of use and Privacy Policy mentioned.. As TNF-alpha and C-reactive protein ( CRP ) [ 44 ] and medicinal plants rhaponticum ), (! Uterine contractions, and without commercial influence, fever, inflammation, and in this case, used... Of dietary fiber medications can also drag and drop the file into the provided field time frame is what lead. China with Chinese people 1980 ; 21 ( 11 ):665-6, 644 cholesterol-lowering, antioxidant, and without influence! Theres also a chance it could interact with other Chinese herbs and plants...

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