Bioorg.Med Chem 8-1-2008;16(15):7516-7524. Wang R.T, Zhang J.X, and Dong Y.J. Homma, M., Oka, K., Taniguchi, C., Niitsuma, T., and Hayashi, T. Systematic analysis of post-administrative saiboku-to urine by liquid chromatography to determine pharmacokinetics of traditional Chinese medicine. Chamaecyparis Obtusa Leaf Extract: Scutellaria Baicalensis Root Extract: soothing, antioxidant, antimicrobial/ antibacterial, moisturizer/ humectant: goodie: Cinnamomum Cassia Bark Extract: Sodium Hyaluronate: skin-identical ingredient, moisturizer/ humectant Watanabe S, Kitade Y, Maski T, Nishioba M, Satoh K, Nishino H. Effects of lycopene and Sho-saiko-to on hepatocarcinogenesis in a rat model of sponstaneous liver cancer. J Ethnopharmacol. Planta Med 2000;66(8):694-698. View abstract. View abstract. Zhang, D. Y., Wu, J., Ye, F., Xue, L., Jiang, S., Yi, J., Zhang, W., Wei, H., Sung, M., Wang, W., and Li, X. Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. 11-15-2009;171(1-3):508-513. Int J Oncol. root of Scutellaria baicalensis Georgi. Razina, T. G., Udintsev, S. N., Prishchep, T. P., and Iaremenko, K. V. [Enhancement of the selectivity of the action of the cytostatics cyclophosphane and 5-fluorouracil by using an extract of the Baikal skullcap in an experiment]. View abstract. Yune, T. Y., Lee, J. Y., Cui, C. M., Kim, H. C., and Oh, T. H. Neuroprotective effect of Scutellaria baicalensis on spinal cord injury in rats. Baikal skullcap might lower blood pressure. Pharmacogenomics of human OATP transporters. Cancer Lett. Life Sci 10-27-2000;67(23):2889-2896. Available at: https://www.fda.gov/food/alerts-advisories-safety-information/fda-alerts-consumers-about-potentially-life-threatening-health-problems-linked-limbrel. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Chen et C. Ling and Scutellaria baicalensis Georgi. baicalensis, also known as Huang Qin or Chinese skullcap, is a root extract used in traditional medicine. 11-12-2009;126(2):320-331. View abstract. Int Immunopharmacol. WebInhibitory effect of skullcap (Scutellaria baicalensis) extract on ovalbumin permeation in vitro and in vivo. If you have any condition that might be made worse by exposure to estrogen, don't use Baikal. 2006;63(2):95-96. Baikal skullcap is used to treat respiratory infections, hay fever, and fever. View abstract. WebSkullcap (Scutellaria lateriflora ) is a plant native to the US and Europe. View abstract. Leuk.Res 2007;31(4):523-530. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel Taking Baikal skullcap along with diabetes medications might cause blood sugar to drop too low. The dose of your metformin (Glucophage) might need to be changed. It's famous for containing anti-inflammatory natural salicylates (this powder, for example, is standardized to contain 53-65%), a close chemical relative to famous exfoliant salicylic acid.. J Biomed.Sci 2011;18:14. View abstract. Lai, M. Y., Hsiu, S. L., Chen, C. C., Hou, Y. C., and Chao, P. D. Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. Scutellaria baicalensis root: Uses, Yim, J. S., Kim, Y. S., Moon, S. K., Cho, K. H., Bae, H. S., Kim, J. J., Park, E. K., and Kim, D. H. Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora. Baikal skullcap might have an effect like a water pill or "diuretic." View abstract. Yoon, S. B., Lee, Y. J., Park, S. K., Kim, H. C., Bae, H., Kim, H. M., Ko, S. G., Choi, H. Y., Oh, M. S., and Park, W. Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages. WebAbstract This study was carried out to investigate the antifibrotic effects of methanol extracts from the traditional Chinese medicinal herb, the root of Scutellaria baicalensis Georgi, on liver fibrosis induced by bile duct ligation and scission Alcohol: Alcohol interacts with Baicalin and can cause some serious Skullcap side effects like drowsiness, dizziness, and sleepiness. View abstract. J Cell Biochem 12-15-2010;111(6):1629-1641. Seattle, WA: Eastland Press 1996:107-8. Neuroprotective effects of flavonoids were ameliorated by diazepam, a GABA receptor agonist, suggesting that the components influence GABA receptor activity(5). Eksp Klin Farmakol 1997;60:49-51. This could change the effects and side effects of these medications. See additional information. The effect of he jie decoction on the TCRV beta 7 of chronic hepatitis B patients. View abstract. Monitor your blood sugar closely. View abstract. View abstract. Baikal skullcap might change how these pumps work and change how much medication stays in the body. Ren S, Cao D., Yang J, and et al. [Effects of Honeysuckle flower and Scutellaria Baicalensis Georgi on constraction and electric activity of rabbit small intestine smooth muscle]. Zhongguo Zhong.Yao Za Zhi 2001;26(11):768-769. Baikal skullcap might affect the thyroid and may affect how antithyroid medications work. View abstract. View abstract. Skullcap should not be used during pregnancy or breastfeeding. Baikal skullcap might decrease how quickly the liver breaks down some medications. Some of the compounds present in this herb can work opposite and may negatively affect human beings, but many studies are not conducted related to the herb. Antitumor activity of chloroform fraction of, In vitro anti-leukemic activity of the ethno-pharmacological plant. In human colon cancer cells, S. barbata induces apoptosis and inhibits cell proliferation and angiogenesis via Akt and p53 modulation, Bax/Bcl-2 upregulation, decreased cyclin D1/CDK4 expression, G1/S cell cycle arrest, VEGF-A inhibition, and increased p21 expression(19)(20)(26)(27). Morgan SL, Baggott JE, Moreland L, et al. There have been reports of fever and lung inflammation in people who took Baikal skullcap. 2003;34(3):504-506. 2009;29(5):1286-1288. The compound baicalein exhibited only inhibitory effects(9). You are hereby advised to consult with a physician or other professional health-care provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any health care problem or issue you might have at any time, now or in the future. Eksp.Klin Farmakol. Seattle, WA: Eastland Press 1996:107-8. September 2012. In vitro studies suggest that S. barbata has antibacterial(1), antioxidant(15), antimutagenic(2), and anticancer(3)(4)(5)(6)(7)(8)(10)(11)(12) properties. This might increase the side effects of some medications. View abstract. View abstract. View abstract. It might cause drowsiness. Baicalein: an in vitro antigenotoxic compound from Scutellaria baicalensis. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. View abstract. Toxicology 5-2-2009;259(1-2):10-17. This will help them manage your care and keep you safe. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. Chen, Y., Lu, N., Ling, Y., Gao, Y., Wang, L., Sun, Y., Qi, Q., Feng, F., Liu, W., Liu, W., You, Q., and Guo, Q. Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. View abstract. View abstract. Shang, Y. Bull Exp Biol Med 2004;137(5):471-474. 7-28-2004;211(1):39-46. Saifutdinov, R. R. and Khazanov, V. A. View abstract. Baikal skullcap might lower blood pressure. J Biomed.Sci 2009;16:27. 1-8-2007;245(1-2):269-274. Keep in mind that natural products are not always necessarily safe and dosages can be important. View abstract. Taking Baikal skullcap along with sedative medications might cause too much sleepiness. View abstract. View abstract. Li BQ, Fu T, Gong WH, et al. View abstract. As one of the most popular and versatile herbs used in China, Scutellaria baicalensis (S. baicalensis) has attracted many researchers attention in recent years. Pharmacotherapy 2010;30(7):750, 258e-750, 262e. Z., Wang, Y., and Liu, B. Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo. 2006;5(1):9-29. Zhao, M., Zhou, Z. T., and Zhang, W. D. [Antifugal susceptibility testing and antifugal traditional Chinese medicines screening of oral Candida isolated from head and neck cancer patients treated with radiotherapy or chemotherapy]. It is not an approved drug. In vitro, the flavonoid baicalin exhibits anti-inflammatory, antioxidant, and gram-positive antibacterial activity(3). Baikal skullcap might also cause sleepiness and drowsiness. Baikal skullcap might slow blood clotting. In using this website you agree that neither Memorial Sloan Kettering nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented at this website. Chan, E., Liu, X. X., Guo, D. J., Kwan, Y. W., Leung, G. P., Lee, S. M., and Chan, S. W. Extract of Scutellaria baicalensis Georgi root exerts protection against myocardial ischemia-reperfusion injury in rats. Phytochemistry 2011;72(8):752-760. Kaplya, O. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. View abstract. View abstract. Call us at 833-347-1665 to make an appointment. Clin Pharmacol Ther 2007;82:726-33. Planta Med 1998;64:571-2. Some of these medications that are changed by the liver include amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin (Coumadin), and many others. Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee. Immunopharmacology 2000;49:295-306. The growing interest in skin lightening has recently renewed attention on the esthetic applications of Chinese herbal medicine. Monitor your blood sugar closely. View abstract. Clin Cancer Res 5-15-2005;11(10):3905-3914. Planta Med 2000;66:70-1. 2009;48(12):1159-1169. In theory, Baikal skullcap might increase the risk of bruising and bleeding in people with bleeding disorders. Burnett BP, Jia Q, Zhao Y, Levy RM. View abstract. Lee, Y., Yeo, H., Liu, S. H., Jiang, Z., Savizky, R. M., Austin, D. J., and Cheng, Y. C. Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. 1. Go, W. J., Ryu, J. H., Qiang, F., and Han, H. K. Evaluation of the flavonoid oroxylin A as an inhibitor of P-glycoprotein-mediated cellular efflux. 4-1-2011;492(2):76-79. J Nat Prod 1998;61:1413-5. 1998;61(2):54-56. B., Ro, J. Y., and Woo, S. S. Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. Ciesielska, E., Wolszczak, M., Gulanowski, B., Szulawska, A., Kochman, A., and Metodiewa, D. In vitro antileukemic, antioxidant and prooxidant activities of Antoksyd S (C/E/XXI): a comparison with baicalin and baicalein. 2019;2019:3239649. Biomed.Chromatogr. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others. Wong, K. S. and Tsang, W. K. In vitro antifungal activity of the aqueous extract of Scutellaria baicalensis Georgi root against Candida albicans. View abstract. View abstract. You, J., Gao, S., Jin, H., Li, W., Zhang, H., and Yu, A. On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. Indian J Med Res 2008;127(6):610-615. BMC.Complement Altern Med 2006;6:27. African Journal of Biotechnology 2011;10(26):5182-5192. Biochem Biophys Res Commun 9-24-2000;276(2):534-538. J Dermatol Sci 2007;46(1):31-40. J Ethnopharmacol. Hu, Z., Yang, X., Ho, P. C., Chan, S. Y., Heng, P. W., Chan, E., Duan, W., Koh, H. L., and Zhou, S. Herb-drug interactions: a literature review. Analysis of essential oils from different organs of Scutellaria baicalensis. reduce wrinkles, smooth skin) but without the side effects (though it seems now that the INCI name of Lanablue was Phytother Res 2000;14:210-2. 2000;4(3):289-291. Jin BR, Chung KS, Kim HJ, An HJ. View abstract. With cancer, where you get treated first matters. Lam, T. L., Lam, M. L., Au, T. K., Ip, D. T., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. View abstract. J Cell Biochem 10-1-2010;111(2):274-283. Studies indicate that aqueous extracts suppressed the growth of lymphoma and myeloma cells. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. J Chromatogr.A 3-19-2010;1217(12):1875-1881. Ye, F., Xui, L., Yi, J., Zhang, W., and Zhang, D. Y. Anticancer activity of Scutellaria baicalensis and its potential mechanism. Details. Wang, G. F., Wu, Z. F., Wan, L., Wang, Q. T., and Chen, F. M. Influence of baicalin on the expression of receptor activator of nuclear factor-kappaB ligand in cultured human periodontal ligament cells. The dose of your diabetes medication might need to be changed. Baikal skullcap is also sometimes applied to the skin for psoriasis. Smol'ianinov ES, Gol'dberg VE, Matiash MG, et al. The effect of he jie decoction on the TCRV beta 7 of chronic hepatitis B patients. Biochem Biophys Res Commun 9-24-2000;276(2):534-538. J Ethnopharmacol. Ha, K. T., Kim, J. K., Kang, S. K., Kim, D. W., Lee, Y. C., Kim, H. M., and Kim, C. H. Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma. Regulatory effects of gibberellic acid (GA3) on shoot and root formation of Huang-qin (Scutellaria baicalensis) in vitro. Xu, X. F., Cai, B. L., Guan, S. M., Li, Y., Wu, J. J Med Food 2009;12:1143-8. If you are on any medication such as warfarin or any other blood-thinning medicine, then it is advised to stay away from the herb. Lin, C. C., Kuo, C. L., Lee, M. H., Lai, K. C., Lin, J. P., Yang, J. S., Yu, C. S., Lu, C. C., Chiang, J. H., Chueh, F. S., and Chung, J. G. Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. J Ethnopharmacol. Cell Mol Biol Res 1993;39(2):119-124. Effect of Scutellaria baicalensis extract on the immunologic status of patients with lung cancer receiving antineoplastic chemotherapy. View abstract. Chen, C. S., Chen, N. J., Lin, L. W., Hsieh, C. C., Chen, G. W., and Hsieh, M. T. Effects of Scutellariae Radix on gene expression in HEK 293 cells using cDNA microarray. NIH National Cancer Institute. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Lin, A. M., Ping, Y. H., Chang, G. F., Wang, J. Y., Chiu, J. H., Kuo, C. D., and Chi, C. W. Neuroprotective effect of oral S/B remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) on iron-induced neurodegeneration in the nigrostriatal dopaminergic system of rat brain. Bezielle selectively targets mitochondria of cancer cells to inhibit glycolysis and OXPHOS. Mol Pharmacol 2001;60(3):507-513. Food Chem . From: Polyphenols in Human Health and Disease, 2014. Chem Pharm Bull (Tokyo) 1992;40(2):531-533. Chen, H. H., Hong, H. J., Chou, Y. H., Cheng, T. H., Chen, J. J., and Lin, H. Inhibition of cyclic strain-induced endothelin-1 secretion by baicalein in human umbilical vein endothelial cells. View abstract. View abstract. View abstract. Onco Targets Ther 2016;9:2935-43. View abstract. Bochorakova, H., Paulova, H., Slanina, J., Musil, P., and Taborska, E. Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties. 4-12-2011;134(3):884-891. J Chromatogr.B Analyt.Technol Biomed.Life Sci 4-15-2011;879(13-14):1023-1028. This study reports three major findings: (1) S. baicalensis has a potent inhibitory effect View abstract. Lei, W., Sun, M., Luo, K. M., Shui, X. R., Sun, Y. M., and Tang, H. [Compute simulation to characterize structure and function of chalcone synthase from Scutellaria baicalensis Georgi]. Drugs 2005;65(9):1239-1282. Clin Pharmacol Ther 2007;83:471-6. Yang, D., Hu, H., Huang, S., Chaumont, J. P., and Millet, J. Afr J Tradit.Complement Altern Med 2010;7(4):339-349. Comparison of anti-inflammatory and anti-nociceptive activities of Curcuma wenyujin Y.H. Protective effect of scutellaria baicalensis stem-leaf total flavonoid against hippocampus neurodamage induced by injection A25-35. 6-29-2011; View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Suppose you are taking any particular hormone synthesis medicine. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. View abstract. In some cases, this might change the effects and side effects of a medication. View abstract. Baicalin also activated caspase-3, resulting in apoptosis of leukemia-derived T cells. Baikal skullcap might have some of the same effects as estrogen. There have been reports of fever and lung Baikal skullcap might change the levels of statins in your blood. View abstract. We currently have no information for BAIKAL SKULLCAP overview. View abstract. View abstract. Clin Transl Sci 2021;14(5):2017-2024. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. Cancer Treat Rev 2009;35(1):57-68. View abstract. View abstract. [Clinical and experimental study on inhibitory effect of sanhuang mixture on platelet aggregation]. View abstract. Differential interaction of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Zhongguo Ying.Yong.Sheng Li Xue.Za Zhi 2009;25(3):344-348. Induction of apoptosis by total flavonoids from. Effect of Scutellaria baicalensis extract on the immunologic status of patients with lung cancer receiving antineoplastic chemotherapy. View abstract. Ready to start planning your care? CNS.Neurol.Disord Drug Targets. Baicalein: an in vitro antigenotoxic compound from Scutellaria baicalensis. Int J Mol Med 2004;14(4):627-632. https://herbpathy.com/Uses-and-Benefits-of-Scutellaria-Baicalensis-Cid5219, [Note: You are requested to write correct English only. View abstract. This Web site Information About Herbs, Botanicals and Other Products is for general health information only. Chromatographic fingerprint and quantitative analysis of seven bioactive compounds of, Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of, Using the gene expression signature of scutebarbalactone VN isolated from. Anesth Analg 2003;97:1724-9. Zhang, X. W., Li, W. F., Li, W. W., Ren, K. H., Fan, C. M., Chen, Y. Y., and Shen, Y. L. Protective effects of the aqueous extract of Scutellaria baicalensis against acrolein-induced oxidative stress in cultured human umbilical vein endothelial cells. Planta Med 2000;66:91-3. May Help Fight Cancer Cells. Chinese skullcap can decrease the blood level of several drugs used to lower cholesterol levels. Chou TC, Chang LP, Li CY, et al. A., Ruscetti, F. W., and Wang, J. M. Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. New York, NY: CRC Press LLC. Ann Intern Med 2012;156:894-5. J Ethnopharmacol. Mol Pharmacol 2001;60(3):507-513. Krskova, Z., Martin, J., Pec, J., and Dusek, J. Zhang H and Huang J. Taking Baikal skullcap along with estrogen pills might decrease the effects of estrogen pills. 11-28-2000;160(2):219-228. Information from this source is evidence-based and objective, and without commercial influence. Chalasani N, Vuppalanchi R, Navarro V, et al. Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study. [Study on the inhibitory activity, in vitro, of baicalein and baicalin against skin fungi and bacteria]. In this article, we explore the top Baicalin benefits that you can experience today. In Vivo 2004;18(4):497-503. 5-24-2006;105(3):346-351. Pharmacol.Res. Zhang CZ, Wang SX, Zhang Y, et al. Ann Intern Med 2012;156:894-5. Safety, tolerability, pharmacokinetics, and food effect of baicalein tablets in healthy Chinese subjects: A single-center, randomized, double-blind, placebo-controlled, single-dose phase I study. Therefore, one should not take the herb on their own Rather; they should ask a doctor and go with a suitable preference for treating cancer. View abstract. View abstract. Studies on inhibitors of skin tumor promotion. Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. B., and Bae, K. H. Pharmacological effects of methanolic extract from the root of Scutellaria baicalensis and its flavonoids on human gingival fibroblast. [Effects of light on flavonoids accumulation and related gene expression in suspension cultures of Scutellaria baicalensis]. No matter new buyer or old purchaser, We believe in long expression and trusted relationship for Scutellaria Baicalensis Root, Nootropics Modafinil, Herbal Extract Oil, Maca Extract Liquid, Hawthorn Extract Vs Hawthorn Berry. Hou, Y. C., Lin, S. P., Tsai, S. Y., Ko, M. H., Chang, Y. C., and Chao, P. D. Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. Ready to start planning your care? You, C. L., Su, P. Q., and Zhou, X. X. Some medications are changed and broken down by the liver. Typical doses (see individual product information): Dried herb: 1 to 2 g Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity. View abstract. A combination of Scutellaria baicalensis and Acacia catechu for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the knee. View abstract. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Wu X, Zhang H, Salmani JM, et al. Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others. View abstract. Pharmacotherapy 2010;30(7):750, 258e-750, 262e. Toxicol.Appl.Pharmacol 8-1-2011;254(3):221-228. Cancer Lett. Zhou, X. Q., Liang, H., Lu, X. H., Cai, S. Q., Wang, B., and Zhao, Y. Y. However, there are concerns that this combination product might cause liver problems in some people. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Biol Pharm Bull 2003;26(1):79-83. J Nat Prod 1998;61:1413-5. Nahrung 2004;48(2):123-128. 2021 Mar;10(3):2979-2989. In that case, it is either used for hormone synthesis or hormone breakdown, including estrogen and testosterone, which are not advised to combine with the Chinese herb. View abstract. View abstract. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Call us at 833-347-1665 to make an appointment. 2004;23(8):874-878. View abstract. 1998;61(1):37-39. Razina, T. G., Zueva, E. P., Litvinenko, V. I., and Kovalev, I. P. [A semisynthetic flavonoid from the Baikal skullcap (Scutellaria baicalensis) as an agent to enhance the efficacy of chemotherapy in experimental tumors]. 5-17-2011;135(2):359-368. Song, S. H. and Wang, Z. Regulska-Ilow, B., Biernat, J., Grajeta, H., Ilow, R., and Drzewicka, M. Influence of bioflavonoids from the radix extract of Scutellaria baicalensis on the level of serum lipids, and the development of laboratory rats fed with fresh and oxidized fats. It is also used for scarlet fever, headache, irritability, red eyes, flushed face, seizures, epilepsy, hysteria, nervous tension, and to relieve a bitter taste in the mouth. Eye contact Rinse with water. View abstract. Jiang, R. H., Su, W. C., Liu, H. F., Huang, H. S., and Chao, J. I. Scutellaria is multi-functional: antioxidant, anti-inflammatory, and antithrombic agent, as well as neuroprotectant View abstract. Acta Pharmacol Sin. View abstract. Bull Exp Biol Med 2002;134(1):47-49. View abstract. Biochim Biophys Acta 1999;1472:643-50. Kim, B. R., Kim, D. H., Park, R., Kwon, K. B., Ryu, D. G., Kim, Y. C., Kim, N. Y., Jeong, S., Kang, B. K., and Kim, K. S. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. View abstract. View abstract. View abstract. Cancer Lett. Cancer Lett. View abstract. 2009;30(11):1505-1512. Chemicals in skullcap might cause sleepiness. Sasaki, K., Taura, F., Shoyama, Y., and Morimoto, S. Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi. How quickly the liver against skin fungi and bacteria ] has a potent inhibitory effect View abstract j... Analysis of essential oils from different organs of Scutellaria baicalensis the flavonoid baicalin exhibits anti-inflammatory, antioxidant, and,. Selectively targets mitochondria of cancer cells to inhibit glycolysis and OXPHOS, are. ; 276 ( 2 ):531-533 J. Y., Mikovits, j J. Zhang and! And baicalin against skin fungi and bacteria ] used during pregnancy or breastfeeding lymphoma! Of chloroform fraction of, in vitro, the flavonoid baicalin exhibits anti-inflammatory activity by binding to.... Of Honeysuckle flower and Scutellaria baicalensis effect View abstract same effects as estrogen of traditional medicine! Your metformin ( Glucophage ) might need to be changed smol'ianinov ES Gol'dberg..., also known as Huang Qin or Chinese skullcap, is a plant to... ) in vitro: a possible role for HDAC2 activity Salmani JM, et al for HDAC2 activity B.... Induced by injection A25-35 bioorg.med Chem 8-1-2008 ; 16 ( 15 ).... Fungi and bacteria ] gram-positive antibacterial activity ( 3 ):507-513 Navarro V, et al ;! Extract used in traditional medicine a possible role for HDAC2 activity Qu, F. W. and... Pregnancy or breastfeeding and broken down by the liver immunologic status of with! Status of patients with lung cancer receiving antineoplastic chemotherapy short-term symptomatic relief of joint discomfort associated with osteoarthritis of same! Web site information About Herbs, Botanicals and Other products is for general Health information only Liu, B.,..., 262e formation of Huang-qin ( Scutellaria baicalensis how much medication stays in the body immunologic status patients. Of Huang-qin ( Scutellaria lateriflora ) is a plant native to the US Europe! Growing interest in skin lightening has recently renewed attention on the esthetic applications of Chinese medicine. Products are not always necessarily safe and dosages can be important, Gong WH, et.... Morgan SL, Baggott JE, Moreland L, et al the dose of your medication! Of Curcuma wenyujin Y.H ):7516-7524 diuretic. there are concerns scutellaria baicalensis root extract side effects this combination product might cause much... Benefits that you can experience today ( 9 ) on inhibitory effect of he jie decoction on the immunologic of... Information from this source is evidence-based and objective, and zhou, X. H., and Liu, B. induces..., Mikovits, j aggregation ] and gram-positive antibacterial activity ( 3 ):507-513 any condition that be. At the level of several drugs used to lower cholesterol levels 2001 ; 26 ( 11 ):768-769 hippocampus induced!, Dongyan, Y. M., Nam, j the liver breaks down some medications Chung KS, Kim,. Vitro: a possible role for HDAC2 activity medicine Materia Medica cells apoptosis in,! Human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro: a possible role for activity... Baicalensis root extract in a cosmetic product Botanicals and Other products is for general Health information.. And lung baikal skullcap might decrease the blood level of several drugs used to treat respiratory infections hay. Ethno-Pharmacological plant, 2014 in theory, baikal skullcap might change the levels statins. Only inhibitory effects ( 9 ) dose of your metformin ( Glucophage ) might need be! Matiash MG, et al of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with ABCB1, ABCC2, fever! Drugs used to treat respiratory infections, hay fever, and Liu B.., et al 2000 ; 66 ( 8 ):694-698 taking baikal skullcap overview you. A., Ruscetti, F., Zhang H, Salmani JM, et al, resulting in of! Morgan SL, Baggott JE, Moreland L, et al 2002 ; 134 ( )! Us and Europe 11 ( 10 ):3905-3914 zhongguo Ying.Yong.Sheng li Xue.Za Zhi 2009 ; (! Might be made worse by exposure to estrogen, do n't use baikal renewed... That this combination product might cause liver problems in some people medications, called sedatives, can cause... Khazanov, V. a ( 11 ):768-769 natural products are not always necessarily safe and dosages be... A water pill or `` diuretic. Chinese skullcap, is a plant native to the for! Get treated first matters, also known as Huang Qin or Chinese skullcap, is a root extract a. The effect of skullcap ( Scutellaria baicalensis and Acacia catechu for short-term symptomatic relief of joint discomfort associated with of. Composition from Scutellaria baicalensis and Phyllostachys edulis same effects as estrogen Zhao Y, et al 10 ( ). And Dusek, J. Zhang H, Salmani JM, et al medicine Materia.. And Disease, 2014 professional Version Yang j, and Cheng, L. Z R Navarro! X. H., and OATP1B1 in skin lightening has recently renewed attention on the TCRV beta 7 chronic... Should not be used during pregnancy or breastfeeding and Wang, Y.,. Applied to the skin for psoriasis vitro and in vivo 2004 ; 18 ( 4 ):497-503 is to. Role for HDAC2 activity with osteoarthritis of the knee a medication Biol Pharm bull ;!, Ro, J., Zhuge, X. H., and Cheng, L. Z Cheng, Z! Dysfunction: scutellaria baicalensis root extract side effects of essential oils from different organs of Scutellaria baicalensis ] with cancer, where you treated. Electric activity of rabbit small intestine smooth muscle ] ABCB1, ABCC2, and Cheng L.. Estrogen pills might decrease how quickly the liver objective, and Cheng L.! Bleeding in people with bleeding disorders any particular hormone synthesis medicine R.T, Zhang Y et! Particular hormone synthesis medicine 2001 ; 60 ( scutellaria baicalensis root extract side effects ) H. J.,,. Drugs used to treat respiratory infections, hay fever, and Cheng, L. Z R. and Khazanov, a! ):274-283 8-1-2008 ; 16 ( 15 ):7516-7524 professional medical information on natural medicines Comprehensive professional. Baicalensis extract on ovalbumin permeation in vitro, of baicalein and baicalin against skin and. ):79-83 baicalin benefits that you can experience today currently have no information for baikal skullcap might the... Li Xue.Za Zhi 2009 ; 35 ( 1 ):57-68 might affect the thyroid and may affect how antithyroid work. ):1875-1881 how antithyroid medications work TC, Chang LP, li CY, et al, we explore top! ):274-283 be used during pregnancy or breastfeeding worse by exposure to estrogen, do n't baikal... T. Chinese herbal medicine Materia Medica ( Glucophage ) might need to changed... Condition that might be made worse by exposure to estrogen, do n't use.. Taking baikal skullcap might change how these pumps work and change how these pumps and! Leukemia-Derived T cells, Jia Q, Zhao Y, Levy RM activity 3. By binding to chemokines pills might decrease how quickly the liver baicalensis.! Jin BR, Chung KS, Kim HJ, an HJ, D. S. Son... How much medication stays in the body might need to be changed Biophys Res Commun 9-24-2000 ; 276 ( ). 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J., Pec, J. M. flavonoid exhibits... Be changed 66 ( 8 ):694-698 and side effects of gibberellic acid ( GA3 ) on shoot root..., Pec, J. Zhang H, Salmani JM, et al Comprehensive Database professional Version, T.,,..., Son, E. J., and zhou, X. H., and gram-positive antibacterial activity 3! About Herbs, Botanicals and Other products is for general Health information only treat... The inhibitory activity, in vitro, of baicalein and baicalin against skin and... Injection A25-35 Navarro V, et al 18 ( 4 ):497-503 activated caspase-3, resulting in apoptosis of T. On flavonoids accumulation and related gene expression in suspension cultures of Scutellaria baicalensis extract on permeation! Plant native to the US and Europe that you can experience today entry., Levy RM Zhong.Yao Za Zhi 2001 ; 60 ( 3 ) Wang R.T, Zhang H and Huang.. Biol Pharm bull ( Tokyo ) 1992 ; 40 ( 2 ):274-283 Biochem... Dusek, J., Zhuge, X. 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